Carbohydrate-Based Vaccines. From Concept to Clinic

A. Krishna Prasad


Balsavo 0

Pilna kaina: 125.35 €   10% nuolaida perkant internetu   Sutaupote: 12.54 €

112.81 €

Ypatybės ir aprašymas
AutoriusA. Krishna Prasad
Leidimo metai2019
LeidėjasOUP USA
Leidinio kalbaanglų kalba

The past three decades have witnessed the development and regulatory approval of glycoconjugate vaccines against several medically important bacterial pathogens, including Haemophilus influenzae type b, Streptococcus pneumoniae, Neisseria meningitides, and Salmonella typhi. Immunologic protection against these and many other bacterial diseases is mediated through opsonophagocytic antibodies directed against the surface carbohydrates that define the bacterial serogroup or serotype and serve as virulence factors. These vaccines are composed of bacterial capsular polysaccharides chemically conjugated to immunogenic carrier proteins. Given that the diseases caused by these bacterial pathogens are most pronounced in infants and young children, the development of the glycoconjugate vaccine technology has had a considerable impact on public health.

Many of the chapters in this volume were assembled as a follow-up from a symposium entitled “Carbohydrate-Based Vaccines and Adjuvants” which took place at the 254th American Chemical Society National Meeting held in Washington, DC (August 2017). The symposium was sponsored by Pfizer and the Carbohydrate (CARB) and Biotechnology (BIOT) divisions. This book, therefore, reflects the importance of this field toward design, development, manufacture and licensure of the complex carbohydrate-based (glycoconjugate) vaccines.

The book has been organized into thirteen chapters, which cover a comprehensive landscape including the clinical history, design, development, chemistry, manufacturing and control (CMC) aspects, pre-clinical assays, adjuvants and the various approaches used to develop carbohydrate-based vaccines.

Komentarai (0)

Rašykite komentarą apie šią knygą


El. Paštas


* - pažymėtus laukus užpilyti būtuna

Panašios knygos
Neorganinės chemijos pagrindai. Teorija, praktika, uždaviniai, Vitalijus Janickis, Nijolė Kreivėnienė

Vitalijus Janickis,...

Neorganinės chemijos pagrindai...

Pilna kaina: 19.80 €

5 % nuolaida perkant internetu

18.81 €

Chemijos enciklopedija, Albertas Broga

Albertas Broga

Chemijos enciklopedija

Pilna kaina: 29.50 €

5 % nuolaida perkant internetu

28.02 €



Krepšelis kol kas tuščias

Pagalba perkančiam

10-18 val. darbo dienomis

Facebook draugai



Neorganinės chemijos pagrindai. Teorija, praktika, uždaviniai

AutoriusVitalijus Janickis, Nijolė Kreivėnienė
Leidimo metai2009
Leidinio kalbalietuvių kalba
Pristatymo terminas Lietuvoje 1-3 darbo dienos

Chemijos enciklopedija

AutoriusAlbertas Broga
Leidimo metai2015
Leidinio kalbalietuvių kalba
Pristatymo terminas Lietuvoje 1-3 darbo dienos