- Titulinis
- Visos kategorijos
- Dalykinė ir mokslinė literatūra
- Ekonomika, finansai, vadyba
- Kitos ekonomikos ir verslo knygos
- Concepts and Models for Drug Permeability Studies
![Concepts and Models for Drug Permeability Studies - Humanitas](https://www.humanitas.lt/uploads/_CGSmartImage/no-cover-2f803130014a29326b57c421f6b58da5.png)
José Das Neves
Concepts and Models for Drug Permeability Studies
Balsavo 0
ISBN: 9780443155109
Autorius : José Das Neves
Leidimo metai: 2024
Leidėjas: Woodhead Publishing
Leidinio kalba: Anglų
Formatas: Kieti viršeliai
Formatas: 9×6
Autorius : José Das Neves
Leidimo metai: 2024
Leidėjas: Woodhead Publishing
Leidinio kalba: Anglų
Formatas: Kieti viršeliai
Formatas: 9×6
Kaina:
Šių parametrų produkto neturime
Likutis pakankamas
Pristatymo terminas Lietuvoje 3-6 savaitės
Pristatymo terminas Lietuvoje 1-4 darbo dienos. Galimas nedidelis vėlavimas
Pristatymo terminas Lietuvoje 3-6 savaitės
Pristatymo sąlygos
Aprašymas
<p><i>Concepts and Models for Drug Permeability Studies: Cell and Tissue Based in Vitro Culture Models, </i>Second Edition, summarizes the most important developments in in vitro models for predicting the permeability of drugs. This book is structured around three different approaches, summarizing the most recent achievements regarding models comprising (i) immortalized cells with an intrinsic ability to grow as monolayers when seeded in permeable supports, (ii) primary cells isolated from living organisms and directly cultured as barrier monolayers, and (iii) tissue-based models constructed with cell lines and extracellular matrix that resembles the tridimensional structure of mucosae and other biological membranes, or animal/patient-derived tissues. Each model is covered in detail, including the protocol of generation and application for specific drugs/drug delivery systems. The equivalence between in vitro cell and tissue models and in vivo conditions is discussed, highlighting how each model may provisionally resemble different drug absorption route. Chapters included in the first edition were updated with relevant data published in recent years, while four new chapters were included to reflect new emerging directions and trends in drug permeability models.</p> <p><i>Concepts and Models for Drug Permeability Studies: Cell and Tissue Based in Vitro Culture Models, </i>Second Edition<i>,</i> is a critical reference for drug discovery and drug formulation scientists interested in delivery systems intended for the administration of drugs through mucosal routes and other important tissue barriers (e.g. the BBB). Researchers studying mucosal biology can use this book to familiarize themselves and exploit the synergic effect of mucosal delivery systems and biomolecules.</p>
Atsiliepimai (0)
Palikite atsiliepimą